We’re verging on peak-Jason Calacanis today, I realize. But I wanted to highlight one interesting nugget that was buried in our two and a half hour, no-holds-barred conversation: Calacanis wondered aloud why Yammer founder and PayPal mafia member David Sacks isn’t being considered to be CEO of Microsoft.

He went further saying that Sacks is the clear “Marissa Mayer of Microsoft” because of his understanding of product and leadership. And then he went even further, saying Sacks would have an even bigger impact on Microsoft than Mayer has had on Yahoo.

I wasn’t convinced, arguing that a Microsoft management team and workforce and culture built under Steve Ballmer may just be too alien to a died-in-the-wool startup guy like David Sacks. Furthermore, Mayer at least had been a senior executive at one of the world’s largest internet companies before trying to fix another one.

But, then again, David Marcus is doing it with PayPal… It would be an amazing new trend if pure-startup guys with no big company experience all started to take flailing giants over.